I joined specifically for this.
EFP's are usually positioned a few meters (like 7-15 or less-I saw the blast spot from one like 4ish meters off the road)) off the road on the shoulder or median. I'm skeptical that anything out there can detect/react to, locate, and destroy an object moving roughly 2,000 meters per second directly at an object a few meters away. Maybe but it seems extremely unlikely. An EFP basically works like a HEAT round, a jerry rigged HEAT round I suppose.
I'm also skeptical about these APS's that can handle daisy chained EFP's (2-3 daisy chained and you're in trouble). Luckily that's rare to see.
And they can be aimed at any spot, the front of a vehicle, the sides, back, whatever. I don't know know a whole lot about the APS but I mean, where would you set it up so it doesn't get in the way of the gunner and can still be able to fire at any side of the vehicle?