I may have overlooked this in previous threads, but would the f-35 inability to supercruise or TVC negatively influence the planes ability to conduct A2A? While I understand that supercruise is relatively insignificant in WVR scenarios and the utility of TVC is debatable in both WVR and BVR situations, it seems as if there is too much emphasis on the f-35s stealth, even going as far as lacking a gun in the B & C varients.
Not really. The F-35 will still be able to accelerate to supersonic speeds for weapon release. Despite "supercruise" abilities, aircraft that can do so do not spend much of their time at supersonic speeds, as supercruising or not, this still burns through fuel very quickly. You should be able to find some information somewhere on range reduction suffered by an F-22 supercruising for long periods.
TVC is not very relevant to the F-35's air to air capability. Going purely by platform comparison (and doing this is fraught with peril, see next paragraph), a combination of amazing situational awareness available to the pilot (far superior to even the F-22) and high off-boresight missiles with lock-on-after-launch capability will trump any perceived advantage conferred by thrust vectoring, every time.
More relevant than all that though is the importance of understanding that winning battles (including achieving air superiority) is chiefly determined not by platform specs, but by battlespace management and achieving synergies between warfighting systems.
My opinion, anyway. Your mileage may vary.